Preheat oven to 450 degrees. Line baking sheet with parchment paper or silicone mats
Rinse cauliflower under running water and shake dry. Remove stems and stalk. Cut into bite-sized pieces.
Combine flour, water, olive oil, garlic powder and salt in a large mixing bowl. Stir until well combined.
Add the cauliflower to the flour mixture and stir gently to coat all the pieces of cauliflower.
Place the coated cauliflower on the baking sheets.
Bake for 15 minutes. Half way through cooking time, remove from oven, flip over cauliflower and return to oven.
While the cauliflower bakes, melt 2 tablespoons of butter. Then mix the butter with the Frank's Hot Sauce.
After 15 minutes, remove the cauliflower from the oven and toss in the buffalo sauce.
Once the cauliflower is well coated in hot sauce, return to the baking sheet and bake another 20-25 minutes, turning halfway through.
Remove from oven and serve while warm.